Patient Blog

Everything You Should Know About Breast Cancer Recurrence

Published on: February 12, 2025 | PocketHealth
Patient getting a breast exam

The possibility of breast cancer recurrence can be stressful, but fortunately, the rates are relatively low and it can often be successfully managed. Additionally, the longer it has been since the initial cancer diagnosis, the lower the chances of recurrence. This guide will cover risk factors, screening methods, symptoms of recurrence and frequently asked questions.

For those looking to take proactive control of their breast health, PocketHealth can help. With secure, easy access to your breast imaging records, PocketHealth allows you to better understand your breast health. In addition, PocketHealth offers personalized estimated breast cancer risk scores to help you and your doctor make informed decisions about preventive measures and future screenings.

 

Access your medical imaging & reports from over 800 hospitals and clinics.

 

What is breast cancer recurrence?

Breast cancer recurrence is when a patient has previously had breast cancer and it returns later. While anyone who has previously had this condition may have a risk of recurrence, most patients will not experience this.

However, if a patient successfully overcomes cancer in one breast and then in the future the other untreated breast develops cancer, this is not categorized as a recurrent cancer. It is treated as an entirely new case and it is frequently termed as second primary breast cancer.

 

Why does breast cancer recurrence happen?

Recurrence can occur if the initial cancer treatment didn’t eliminate all of the cancer cells. Medical treatments and therapies can shrink tumors so much that the remaining weakened cells are undetectable on tests. If any cancer cells remain, they may grow and cause new tumors over time.

Additionally, if cancer cells spread to other areas, such as the bloodstream or lymph nodes, they may return and lead to recurrence. Overall, recurrence is most common within the first two years after initial treatment, though it can happen later, albeit rarely.

 

Types of breast cancer recurrence

There are three types of breast cancer recurrence, which may affect treatment decisions, imaging methods and additional testing.

Local

This occurs when cancer returns to the area where the original tumor was located, such as the breast tissue or, in cases where a mastectomy was performed, the chest wall. Treatment may be similar to how the initial cancer was addressed, including assessing factors like hormone receptors.

Depending on specifics such as tumor grade, size and stage, more aggressive treatment may be necessary. For example, if a lumpectomy was done for the first occurrence, a mastectomy may be recommended for the recurrence. Since each patient is unique, there is no one-size-fits-all approach. Patients should consult their doctor to determine the best course of action.

Regional

Regional cancer recurrence occurs when the disease returns near the original tumor, often around the collarbone or in the underarm (axillary) lymph nodes. While it remains local to the general area of the first cancer, it has spread to nearby regions rather than the exact location of the original tumor.

Distant (Metastasis)

When breast cancer recurs, it may spread to other areas of the body, such as organs or bones. This can make treatment more challenging, so patients need to discuss their options with their doctor, including exploring new clinical trials or targeted therapy approaches. Fortunately, the majority of recurrent breast cancer cases remain local and do not develop metastatic lesions.

 

Symptoms of breast cancer recurrence

Symptoms may vary depending on where the new cancer cells are located in relation to the original tumor. Local cancer may cause different symptoms compared to cancer that has spread to the lymph nodes, as seen with regional recurrence. Here are some general symptoms of recurrence, keeping in mind that some are more likely to occur with specific types:

  • Nipple changes: This can include changes in appearance or discharge.
  • Breast lumps: These may be discovered during a breast exam.
  • Skin changes: If the patient had a lumpectomy, the skin near the area may show signs of pulling, thickening or swelling. Abnormal breast firmness is another possibility.
  • Chronic pain in the chest or armpit: This could indicate lymph node involvement and may also affect the collarbone or shoulder.
  • Swallowing problems: This includes difficulty swallowing or a chronic dry cough.
  • Unusual and severe fatigue: Especially if it is persistent and chronic.
  • Unexplained weight loss: Changes in appetite and nausea are also important to note.
  • Other unexplained symptoms: Distant recurrence can affect other areas of the body, leading to a wide range of symptoms in different locations.

 

How is breast cancer recurrence discovered?

Breast MRI

A breast screening MRI

Recurrence is typically discovered using similar methods to those used for the initial cancer diagnosis. However, patients with a history of cancer are often recommended to undergo screenings and tests more frequently than those who have never experienced the disease. Here are some common screening and diagnostic methods.

Breast exam and breast changes

Performing a self-breast exam to feel and look for changes can be helpful in detecting tumors and other symptoms. Some patients may also receive a breast exam as part of their routine annual check-up with their doctor.

Mammogram or other imaging

The most common breast cancer screening is through mammograms, but other types of imaging can be helpful too. Often, cancer patients receive these scans more frequently than those who have never had cancer. Some of the common methods for this include:

  • 2D or 3D mammograms: 2D mammograms are the current standard method, with two X-ray images taken of each breast. However, 3D mammograms may be recommended for patients with dense breasts or other factors requiring additional detail, as they capture far more images.
    Breast ultrasound: While not as detailed as some other imaging methods, breast ultrasounds are useful for determining whether a breast lump is a fluid-filled cyst or a solid tumor.
  • Breast MRI: Breast MRIs provide a level of detail that many other scanning methods lack, especially when a contrast agent is used to better differentiate anatomical structures.
  • CT and PET scans: Computed tomography (CT) and positron emission tomography (PET) scans are additional methods that may use contrast agents for enhanced detail. PET scans are particularly useful for detecting if cancer has spread to other areas.

Blood tests for tumor markers

Tumor markers refer to substances created by cells as a reaction to cancer. These substances are typically present in low quantities in most people, but a significant increase may suggest the presence of certain cancers. However, not all cancers produce tumor markers, and high levels do not always indicate cancer. Tumor markers are primarily a starting point, after which further testing is needed to confirm or rule out the presence of the disease.

Biopsy

The standard method for an official breast cancer diagnosis is typically a biopsy. This procedure involves using a thin needle to remove a small tissue sample for analysis. In some cases, an MRI or other imaging technique is used to guide the needle to the exact location being tested. There are variations of the biopsy procedure depending on the location of the tumor and the size of the sample needed.

 

Next steps for returning breast cancer

If breast cancer recurrence is confirmed, treatment will depend on factors such as:

  • Hormone receptors: If the cancer has hormone receptors, it means the cancer cells are using certain hormones to fuel their growth. Hormone therapy can be an effective way to slow or stop this growth.
  • Cancer spread: If the cancer has spread, treatment may differ. However, even if the cancer has metastasized, it is still considered breast cancer and will be treated as such.
  • HER2-positive breast cancer: The human epidermal growth factor receptor 2 (HER2) gene is important in some breast cancer cases. When the HER2 gene mutates, it produces excess HER2 proteins, which can cause cancer cells to grow and spread quickly. Treatment specifically targets HER2 to help slow or stop cancer growth.
  • Cancer grade: The cancer grade reflects how different the cancer cells are from normal breast tissue. Particularly differentiated cells may indicate faster growth, which can influence the methods and timing of treatment.

How is recurrent breast cancer treated?

Specific treatment will depend on factors mentioned above. Here are some general methods to be aware of:

  • Radiation therapy: This is the use of high-energy rays that destroy cancer cells.
  • Hormone therapy: Hormone blocking treatments can prevent cancer cells from using them as fuel for growth.
  • Immunotherapy: This method helps to boost the patient’s own immune system, to better fight off cancer cells.
  • Targeted therapy: These help to block the excess growth of HER2 proteins.
  • Chemotherapy: Cancer fighting medication to help kill these cells or stop their growth.
  • Surgery: Examples include removal of the tumor or performing a mastectomy.
  • Pain management: For patients experiencing discomfort, there are several medications to help improve comfort and fatigue.

 

Getting my results

A 2D mammogram

A 2D screening mammogram

Turnaround times for breast imaging results can vary widely depending on the facility and your doctor’s availability. Often, patients wait a week or more and receive their results during a follow-up appointment. With PocketHealth, you don’t have to wait as long—your results are available securely as soon as they’re uploaded, allowing you to review them often before your follow-up visit.

When you do gain access to your results, it’s common to find medical terminology somewhat confusing, but Report Reader helps you to better understand your report by offering clear, straightforward definitions for medical terms—simply tap or click on any underlined words to reveal their meaning.

 

Access your medical imaging & reports from over 800 hospitals and clinics.

 

Frequently asked questions

Here are some common questions regarding breast cancer recurrence.

What is the survival rate for breast cancer recurrence?

While treating recurrent breast cancer can sometimes be more complex, it doesn’t necessarily mean the prognosis is worse than the first time. Possible outcomes depend on several factors, which vary by individual. The patient’s medical provider will likely have the most knowledge of their specific case. Generally, the earlier the recurrence is diagnosed, the easier it is to treat. Fortunately, most medical providers regularly screen previous cancer patients, so if signs of recurrence appear, it can be addressed early.

Are there any complications with breast cancer recurrence?

Complications depend on factors such as the cancer’s stage, grade and whether it has metastasized. Recurrent cases may require more intensive treatments, but this doesn’t necessarily indicate a worse prognosis. It may simply mean a different or more varied approach than the initial treatment. Ultimately, much depends on the individual and their specific case.

Which type of breast cancer is most likely to recur?

Triple-negative breast cancer and inflammatory breast cancer are the two types most likely to recur later. These types are less common than other forms of breast cancer. Triple-negative breast cancer accounts for 10 to 15% of all cases, while inflammatory breast cancer is even rarer, making up 1 to 5% of all cases.

What is the breast cancer recurrence after a mastectomy?

If a patient had a mastectomy for their initial breast cancer diagnosis, the cancer may still recur in the chest region. However, the recurrence rate is low. About 5% of patients who have had a mastectomy will experience recurrence within 12 years.

Is there anything I can do to lower my risk of breast cancer recurrence?

There are several recurrence risk factors related to the type and grade of the initial cancer and treatment types, such as radiation or a mastectomy. However, there are some steps that patients may consider to potentially lower their risk:

  • Hormone medications: Certain medications, like tamoxifen or other treatments for hormone-sensitive cancers, may lower the recurrence risk. Patients’ medical providers will help determine if this is a suitable option.
  • Exercise and healthy diet: Regular physical activity and eating a healthy diet have been shown to reduce the risk of recurrence. Ask your doctor for recommendations on which foods to include or avoid.
  • Attend regular screenings: Patients with a history of cancer are often recommended to have frequent breast screenings and follow-up appointments. Following these recommendations may help detect any potential recurrences early, when they are easier to treat.

 

Getting support

The possibility of breast cancer recurrence can feel overwhelming and stressful, but remember, you’re not alone. Often, successful treatment for recurring cancer can eliminate the disease, allowing many patients to return to a normal life. The earlier these cases are detected, the more likely this outcome will be.

Regardless of the type or severity of recurrence, reaching out to support services and connecting with other breast cancer survivors can be helpful. Here are some support organizations that may assist patients in navigating their health journey:

  • The Susan G. Komen Foundation: They provide financial assistance, educational resources and tips for getting through treatments.
  • Breast Cancer Now: A breast cancer research and support charity.
  • SurvivingBreastCancer.org: They offer research information, seminars, online groups and even meditation and expressive writing classes.
  • Local resources: Your doctor will likely have local breast cancer support information.

 

Take control of your breast health journey

Given the repetitive nature of breast imaging, tracking changes over time is essential. Having secure access to all your imaging records in one place allows you to be actively involved in your health journey. You can compare breast changes, send records to other medical providers, and even print and store these reports for your own use. For Mary, accessing her breast imaging through PocketHealth helped her catch the medical recommendation for more frequent mammogram screenings, something her clinic had missed.

Another tool for your breast health is MyCare Navigator, which provides personalized insights to your health and identifies any recommended follow-up steps. This feature can also generate individualized questions to ask your doctor based on the findings in your report, ensuring you make the most of your consultation.

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